The cees dekker Diaries
The cees dekker Diaries
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Rotary motion of DNA rotors on nanopores. Top rated row: raw online video on the Cy5 channel of each rotor. Center row: corresponding single-particle localization effects of the two finishes on the DNA rotors. The position of the present frame is marked as orange and blue dots, and also the trajectory of The ten frames prior to The existing frame is demonstrated as solid traces.
Human Rad51 filaments on double- and single-stranded DNA: correlating common and irregular forms with recombination operate.
Round the identical time, the group of Paul McEuen, who was then dependent on the College of California, Berkeley, showed similar outcomes on ropes of bundled nanotubes. Depending on the wrapping angle, nanotubes can can be found in metallic or semiconducting variants, a prediction that we and Charles Lieber’s group at Harvard College independently confirmed working with scanning tunnelling spectroscopy experiments.
Non-equilibrium folding of personal DNA molecules recaptured approximately one thousand instances within a reliable condition nanopore
Dekker is naast zijn wetenschappelijk werk ook bekend vanwege zijn belangstelling voor de relatie tussen geloof en wetenschap en de discussie rond clever style and design in 2005. (nl)
In the years next these discoveries, my investigate pursuits shifted to biophysics and nanobiology, and I became less linked to the event of nanotube electronics. The main focus of many scientists in the sector also shifted to graphene (wherever, funnily ample, the initial graphene ribbons were called ‘nanotubes that happen to be Minimize open together their size’) following the invention of the two-dimensional material in 2004.
MATLAB codes for info processing are available at . Julia codes useful for numerical simulation can be found at .
Atomic drive microscopy exhibits that vaccinia topoisomerase IB generates filaments on DNA in the cooperative manner
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‘The fantastically delicate way by which elements in mother nature purpose under no circumstances ceases to amaze me. If we fix the puzzle of how existence came into remaining, I be expecting that my amazement with the complexity of development may have amplified and with it my awe for that greatness in the Creator.’
Because 2000 he moved to one-molecule biophysics and nanobiology, with investigation from research of DNA loop extrusion and supercoiling to DNA translocation as a result of nanopores. Additional lately his investigate has centered on studying chromatin framework and cell division with micro organism on chip, whilst he is usually trying to ultimately Create synthetic cells from the bottom up.
Cees Dekker is Distinguished University Professor at TU Delft. Skilled being a physicist, he pioneered nanotechnology with a lot of discoveries on carbon nanotubes from the nineteen nineties. Due to the fact 2000, he moved to one-molecule biophysics and nanobiology. His present-day investigate concentrates on (i) nanopores for protein sequencing; (ii) chromosome framework, specifically SMC motor protein; and (iii) creating a residing synthetic cell from lifeless molecules. Dekker is an elected member of the KNAW and fellow into the APS as well as IOP.
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‘I'm pushed by ponder and thoughts. On a material degree I locate solutions in physics, but I working experience my deepest happiness with God. That faith also drives my science and how I handle men and women.